Search results for " laboratory testin"
showing 6 items of 6 documents
Laboratory testing in the emergency department: an Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) and Academy of Em…
2018
Abstract Background: The mainstay of patient-oriented laboratory testing in emergency settings entails selecting a number and the type of tests according to valid criteria of appropriateness. Since the pattern of urgent tests requesting is variable across different institutions, we designed a joined survey between the Academy of Emergency Medicine and Care (AcEMC) and the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) for reaching tentative consensus about the most informative diagnostic tests in emergency settings. Methods: A survey, containing the most commonly ordered urgent laboratory tests and the relative clinical indications, was disseminated to eigh…
Inappropriateness in laboratory medicine: an elephant in the room?
2017
Appropriateness of diagnostic testing can be conventionally described as prescription of the right test, using the right method, at the right time, to the right patient, with the right costs and for producing the right outcome. There is ongoing debate about the real burden of inappropriateness in laboratory diagnostics. The media coverage of this issue has also recently led to either over- or under-emphasizing the clinical, organizational and economic consequences. This is quite problematic, inasmuch as some reliable data are available in the current scientific literature, showing that inappropriateness of laboratory testing can be as high as 70%. This is especially evident for, though not …
Ether-lipid and docosahexaenoic acid (DHA) levels in erythrocytes of patients with glaucoma
2008
International audience; Purpose: : Neuronal tissues such as the brain and the retina are known to contain elevated amounts of phospholipids with a vinyl-ether double bond (ether-lipids or plasmalogens) as well as high concentrations of long-chain omega-3 polyunsaturated fatty acids (docosahexaenoic acid or DHA). Abnormal blood levels of ether-lipids and DHA have been associated with several neurological disorders such as Alzheimer Disease. Since many observations bring up the idea of pathogenetic similarities between Alzheimer Disease and glaucoma, the aim of our work was to check whether ether-lipid and DHA levels were modified in glaucoma patients. Methods: : Blood samples were collected …
Experimental investigations of the soil–concrete interface: physical mechanisms, cyclic mobilization, and behaviour at different temperatures
2016
Behaviour of the pile–soil interface is important to correctly predict the response of floating piles in terms of displacement and lateral friction. Regarding energy piles, which couple the structural roles of deep foundations with the principle of shallow geothermal energy, the response of pile–soil interfaces is influenced by seasonal and daily cyclic thermal variations. Accordingly, the goal of this paper is to experimentally investigate the response of the pile–soil interface at different temperatures. This experimental campaign aims to analyse (i) the cyclic mobilization of the shear strength of the soil–pile interface that is induced by thermal deformation of the pile and (ii) the di…
Circulating markers of retinal and optic nerve lipids
2013
Purpose Blood lipids are frequently used as a surrogate of lipid composition of peripheral tissues. Even if it is well accepted, such a relationship has never been clearly demonstrated for the eye. The aim of this study was to determine in human samples whether a lipidomic approach based on red blood cells could reveal associations between circulating and ocular lipid profiles. Methods Red blood cells, retinas and optic nerves were collected from 9 human donors. The lipidomic analyses on these tissues were done by both, gas chromatography and liquid chromatography coupled to an electrospray ionization source-mass spectrometer (LC-ESI-MS/MS). Results Gas chromatographic approach did not show…
Design Procedures for Soil-Lime Stabilization for Road and Railway Embankments. Part 2-Experimental Validation
2012
AbstractAs detailed in Part 1, the most common Italian Technical Specifications refer to different design methodologies for design of lime-soil mixtures, some being quite different from those internationally adopted. Therefore, it seemed appropriate to the Authors to compare these methodologies, via a wide experimental program.It is shown that the Italian methodology of the National Road Agency is different not only from those used in Italy, but also from the main international standards. The experimental results highlight that a revision of that methodology is needed in order to bring it into line with what is prescribed by the European standard.